Psychedelic & Dissociation drug's therapeutic potentials?

Psychedelic & Dissociation drug's therapeutic potentials?


What are psychedelic & dissociation drugs?

Psychedelic and dissociative drugs can temporarily alter a person’s mood, thoughts, and perceptions of reality.

Where Used traditionally?

Many psychedelic drugs derive from plants and fungi, and some have been used for thousands of years in traditional or religious rituals. Some psychedelic and dissociative drugs are also synthetic (lab-made).

People report using psychedelic and dissociative drugs for a variety of reasons, including seeking new, fun, healing, or spiritual experiences.

Psychedelic drugs (also called “classic psychedelics” or “psychedelics”), including psilocybin and LSD, mainly interact with specific receptors, which are molecular structures in the brain. Known as 5-hydroxy-tryptamine (5-HT)2A receptors, these are targets for the neurotransmitter (chemical messenger) serotonin. At certain doses, psychedelics may bring on vivid visions or sensations, alter a person’s sense of self, and promote feelings of insightfulness or connection.

Dissociative drugs, including ketamine and PCP, block the action of N-methyl-D-aspartate (NMDA) receptors. These are part of the brain’s system for transporting glutamate, another neurotransmitter. While dissociative drugs can alter perception, they also typically make people feel disconnected from their body and environment.

Other drugs such as MDMA, ibogaine, and salvia work on a variety of brain functions to cause psychedelic or dissociative effects. 

Psychedelic in medical settings

The U.S. Food and Drug Administration (FDA) has approved the ketamine derivative esketamine (under the brand name Spravato®) as a treatment for severe depression in patients who do not respond to other treatments.

Research on to learn whether some of these drugs may help treat substance use disorders in medical settings is going on.


Compiled by 

Ms Naresh kuwar 


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