Candida auris - A significant Global threat.

Candida auris A significant Global threat

Candida auris is an emerging multidrug-resistant yeast that poses a significant global health threat. First identified in 2009, this pathogen has now been isolated in over 60 countries across 6 continents. 

Its association with outbreaks, high mortality rates of 30% to 60%, and frequent misidentification in clinical laboratories, which has prompted the World Health Organization to classify it as a “critical priority” fungal pathogen. 

C auris has since been reported in 61 countries across 6 continents as of 2023.

Transmission

Environmental contamination plays a crucial role in the transmission process. Patients may shed C auris onto surfaces and fomites, including hallways, chairs, beds, windowsills, counters, electrocardiogram leads, blood pressure cuffs, infusion pumps, and ventilators.Shared multiuse equipment, eg, temperature probes and pulse oximeters, may act as reservoirs.

Laboratory studies have shown that C auris can survive on moist or dry surfaces for up to 7 days, with some cells remaining viable for as long as 4 weeks. Strict adherence to isolation protocols and contact precautions plays a vital role in preventing  transmission of C auris. 

Treatment / Management

Concrete documentation of standardized therapeutic options for C auris infection remains absent. Most cases require individualized management, directed by antifungal susceptibility testing. Expert consultation with an infectious disease specialist provides critical guidance in optimizing treatment decisions. 

Complications

A localized infection may eventually become an overwhelming bloodstream infection and have further complications such as sepsis, multi-organ system failure involving the kidneys, heart, lungs, eyes, brain, liver, and spleen, and ultimately death.


Compiled by 

Ms Naresh kuwar







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